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Methods: The Geant4 Application for the Tomographic Emission (GATE) Monte Carlo (MC) package was used, and reconstructed images were obtained by using the software for tomographic image reconstruction (STIR). The accuracy of digital zoom appears equivalent to geometric magnification in diagnosing microcalcifications.īackground: The aim of the present study was to assess the upper information content bound of positron emission tomography (PET) images, by means of the information capacity (IC).The performance of digital zoom is comparable to magnification for detecting microcalcifications when newer detector technology and optimised imaging procedures are utilised.Diagnostic test studies and phantom studies using newer detector technology would contribute additional knowledge on this topic.Key Points The differences between the sensitivities and specificities were not statistically significant.Conclusionsĭigital zoom may be equivalent to magnification mammography. Pooled sensitivity for magnification and zoom calculated from the diagnostic test studies was 0.93 (95% CI 0.84–0.97) and 0.85 (95% CI 0.70–0.94), respectively. Phantom studies suggested that the size of microcalcifications, magnification or zoom factor, exposure factors and detector technology determine whether digital zoom is equivalent to magnification mammography in the detection of microcalcifications. A narrative approach was selected to summarise and compare findings regarding the detection of microcalcifications, while a hierarchical model with bivariate analysis was used for the meta-analysis of sensitivity and specificity for diagnosing microcalcifications.ResultsNine studies were included. Diagnostic test studies, experimental breast phantom studies and a Monte Carlo phantom study were included. We ran an extended search in MEDLINE, EMBASE, CINAHL, Engineering Village and Web of Science. To summarise and compare the performance of magnification mammography and digital zoom utilising a full-field digital mammography (FFDM) system in the detection and diagnosis of microcalcifications.Methods
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